منابع مشابه
Transdermal hyoscine and postoperative nausea and vomiting.
Forty-two patients, undergoing major gynaecological surgery, were randomly allocated to have a patch applied to the skin behind one ear, containing either hyoscine or placebo. They were followed up at 24-hour intervals for 3 days postoperatively and divided into matched pairs for statistical analysis. There was a significant (p less than 0.01) reduction in nausea and vomiting in the first 24 ho...
متن کاملVisual side-effects from transdermal scopolamine (hyoscine).
Transdermal scopolamine may be used to reduce drooling in children with disabilities. Side-effects include dilated pupils and a reduction in the near point of accommodation (the closest point at which clear vision is possible). Two male children with epilepsy, one with spinal dysraphism (aged 7y 6mo) and one with cerebral palsy (aged 5y 8mo), who have undergone treatment for drooling with trans...
متن کاملTransdermal Hyoscine and Postoperative Nausea and Vomiting
Sir,—Koski and colleagues [1] found no difference in the incidence of nausea and vomiting in patients receiving transdennal hyoscine or placebo before operation. This is at variance with the findings of others [2]. A number of points warrant mention. In the study of Koski, different types of surgery were performed, whereas only patients having gynaecological surgery were studied by Uppington, D...
متن کاملTransdermal Patch of Anti-Diabetic Drug
In the present work, monolithic matrix transdermal systems containing Drug x were prepared using various ratios of the polymer blends of hydroxy propyl methyl cellulose (HPMC) and Eudragit S 100 (ES) with triethyl citrate as a plasticizer. A 32 full factorial design was employed. The concentration of HPMC and ES were used as independent variables, while percentage drug release was selected as d...
متن کاملAPI Heterogeneity in a Multilayered Transdermal Patch
Transdermal patches are a popular route for drug delivery because of the sustained drug levels, low side effects, reduced hepatitic first-pass effect and ease of use, including self– administration. The basic components of any transdermal delivery system include one or more active pharmaceutical ingredient s (APIs) dissolved or dispersed in a reservoir or inert polymer matrix; an outer backing ...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 2007
ISSN: 0003-2409,1365-2044
DOI: 10.1111/j.1365-2044.1993.tb06883.x